Bookeen have been showing off their upcoming 5-inch ebook, the Cybook Opus, and it's being met with favor by the e-ink obsessives over at MobileRead. They describe the 150g ebook reader as "positively gorgeous" with excellent ergonomics; the screen doesn't look half bad either, a 200dpi 600 x 800 pixel panel with auto-rotation courtesy of an integrated accelerometer.
The Opus supports ePUB and PDF files, with or without DRM, and has 1GB of internal storage and a microSD card slot for adding more. Since you can fit a whole lot of ebook files into that sort of capacity, you can organize titles into folders. There are large page-turn buttons on the side, apparently making the Opus usable in both portrait or landscape orientations.
The device supports 12 different font sizes and has a user-replaceable battery. Still no word on pricing or specific availability, but there's a full image gallery, plus unboxing photos, available here.