I'm not sure why you would want a suitcase with a sound system inside other than to be able to annoy the hell out of all the people sitting in the terminal waiting for a flight with your tunes. I guess if you are in the hotel room and want to get your dance on, the Trip Sound suitcase might be a good thing.
The Trip Sound weighs in at 13.77 pounds and it measures in at 21.7" x 9.8" x 13.8". It has a handle and wheels so you can pull it through the airport and it has an integrated carry handle as well. The integrated sound system has a pair of 15W speakers on the side of the bag that connect to a digital music player and uses rechargeable power.
The player can play your tunes for over eight hours per charge and the audio input is a 3.5mm headphone port. Other than the sound system, the bag has a place for your clothes and a padded laptop section for your computer. The bag is not cheap though at 750 eur.