Google launched the latest beta version of Chrome (Chrome 21) not long ago. The new beta version adds a couple new APIs to the mix that allow developers a lot more interaction with hardware attached to the computer. Using the new APIs developers can write web applications that are able to use a microphone or camera attached the computer with no need for a plug-in.
Perhaps more interesting for gamers is that developers can now write apps that take advantage of any connected video game controllers. That will certainly make gaming via Chrome much more entertaining when you can use a joystick or game pad to control the action. Since the new APIs are integrated into the browser, no plug-ins, Flash, or Java is needed.