I am not a big fan of staying in hotels. You never know what the sicko's that were in your room did in there before they left. One of the places that germs tend to collect that most of us don’t think about is on the remote control. Any parent will tell you that the remote gets dirty fast with kids around. I know I have had to clean chocolate off my remote more than once.
Gluvi has a new sanitary solution for remote controls that it is aiming at the hotel industry, but the thing could be useful at home too. The Gluvi solution is like a condom for your remote. It appears to be a thin film that slips over the remote and keeps dirty fingers from contaminating the clicker.
The big downside here is that the coating is ugly. I am pretty sure you could do just about the same thing by wrapping your remote in plastic cling wrap too.