While I haven't done this, I'm pretty sure it's possible as I've read a tutorial on it previously and seen various people show it off on YouTube. And some even confirmed it..

However, you need to buy some extra stuff and you have to be willing to risk a Wiimote. If you mess up there's a chance that you might damage the Wiimote.

But once you get it working it should be worthwhile as it would be pretty cool to use a Wiimote on the PC! Imagine playing games with it or browsing such as this with it, it would be like if you were on the Wii Browser, except it would work on PC games. You could play Counter-Strike amongst other FPS games with the Wiimote!